This review offers an overall perspective on how pain is governed by high homeostatic imperatives.
Injuries of various types occur commonly in the lives of humans and other animals and lead to a pattern of persistent pain and recuperative behaviour that allows safe and effective recovery. In this Perspective, we propose a control-theoretic framework to explain the adaptive processes in the brain that drive physiological post-injury behaviour.
https://www.nature.com/articles/s41583-023-00699-5